Who Would Win?

Reed Richards

Scientist, leader of the Fantastic Four

Agility, Stamina, Invulnerability, Intellect, Chameleon, Shape Shifter, Insanely Rich, Elasticity, Unarmed Combat, Gadgets, Size Manipulation, Adaptive, Leadership

Unstable molecules uniform, Ultimate Nullifier, various inventions, Baxter Building lab

Avengers, Challengers of Doom, Cosmic Champions, Council of Doom, Doc Fantastic and his Five for the Future, Fantastic Five, Fantastic Four, Future Foundation, Illuminati, League of Losers, National Aeronautics and Space Administration, Super Hero Squad, The Council, The Initiative, The Vi-Locks, Ultimate Federalist Freedom Fighters, Ultimates

Dione

Conqueror, worshiper of Death

Superhuman Strength, Invulnerability, Energy Projection, Telepathy, Cosmic Awareness, Immortality, Genius-Level Intellect, Infinity Gauntlet

Infinity Gauntlet, Thanoscopter (joke), Double-Bladed Sword

Zodiac (ally); formerly Infinity Watch, Defenders